/*
Theme Name: Crawford Wisdom International
Theme URI: https://www.cfwisdom.com
Author: Crawford Wisdom International
Description: A responsive one-page pharmaceutical enzyme solutions website.
Version: 2.7.0
Text Domain: cfwisdom
*/
:root{--ink:#112c35;--teal:#0d4a51;--deep:#07363d;--mint:#bdf4cf;--lime:#d8ff8e;--cream:#f5f3e9;--white:#fff;--muted:#62777b;--line:rgba(17,44,53,.14)}
@font-face{font-family:"Manrope";src:local("Manrope");font-display:swap}@font-face{font-family:"DM Sans";src:local("DM Sans");font-display:swap}
.brand-logo{width:58px;height:58px;object-fit:contain;display:block}.footer-brand .brand-logo{background:#fff;border-radius:3px;padding:2px}.site-header .brand-logo{mix-blend-mode:multiply}
*{box-sizing:border-box}html{scroll-behavior:smooth}body{margin:0;background:var(--cream);color:var(--ink);font:16px/1.6 "DM Sans",sans-serif;overflow-x:hidden}a{color:inherit;text-decoration:none}h1,h2,h3,p{margin-top:0}h1,h2,h3,.brand{font-family:"Manrope",sans-serif}em{font-family:Georgia,serif;font-weight:400}.site-header{height:88px;display:flex;align-items:center;justify-content:space-between;padding:0 clamp(24px,5vw,78px);background:var(--cream);position:relative;z-index:20;border-bottom:1px solid var(--line)}.brand{display:flex;align-items:center;gap:12px;line-height:1.05}.brand strong{display:block;font-size:16px;letter-spacing:-.3px}.brand small{display:block;text-transform:uppercase;letter-spacing:3px;font:600 8px "DM Sans",sans-serif;margin-top:5px}.brand-mark{width:35px;height:35px;display:grid;place-items:center;position:relative}.brand-mark i{position:absolute;width:27px;height:10px;border:2px solid var(--teal);border-radius:100%;transform:rotate(30deg)}.brand-mark i:nth-child(2){transform:rotate(90deg)}.brand-mark i:nth-child(3){transform:rotate(150deg)}.nav{display:flex;align-items:center;gap:clamp(20px,3vw,45px);font-size:14px;font-weight:600}.nav a:not(.nav-cta){position:relative}.nav a:not(.nav-cta):after{content:"";position:absolute;left:0;right:100%;bottom:-5px;height:1px;background:var(--teal);transition:.25s}.nav a:hover:after{right:0}.nav-cta,.button{display:inline-flex;align-items:center;justify-content:center;gap:22px;padding:14px 19px;background:var(--teal);color:white;font-weight:700;border:0;cursor:pointer;transition:.25s}.nav-cta:hover,.button-primary:hover{background:#11616a;transform:translateY(-2px)}.menu-toggle{display:none;background:none;border:0}.hero{min-height:calc(100vh - 88px);display:grid;grid-template-columns:52% 48%;padding-left:clamp(24px,7vw,110px);background:linear-gradient(110deg,var(--cream) 0 55%,#d9f5df 55% 100%);overflow:hidden}.hero-copy{padding:clamp(72px,9vw,130px) 7vw 48px 0;z-index:2}.eyebrow,.section-kicker{text-transform:uppercase;letter-spacing:2.2px;font-size:11px;font-weight:700;margin-bottom:25px}.eyebrow{display:flex;align-items:center;gap:10px;color:var(--teal)}.eyebrow span{width:24px;height:1px;background:var(--teal)}h1{font-size:clamp(48px,6vw,88px);line-height:.99;letter-spacing:-5px;margin-bottom:28px}h1 em{color:#217861}.hero-copy>p{max-width:590px;font-size:18px;color:#455f64}.hero-actions{display:flex;align-items:center;gap:36px;margin:36px 0 65px}.button{padding:17px 23px}.text-link{font-size:14px;font-weight:700;border-bottom:1px solid var(--ink);padding-bottom:4px}.text-link span{margin-left:18px}.trust-row{display:flex;gap:44px;padding-top:22px;border-top:1px solid var(--line);max-width:650px}.trust-row strong,.trust-row span{display:block}.trust-row strong{font-size:13px}.trust-row span{font-size:11px;color:var(--muted)}.hero-visual{position:relative;min-height:620px;background:radial-gradient(circle at 46% 45%,rgba(255,255,255,.95),rgba(189,244,207,.4) 35%,transparent 63%)}.orb{position:absolute;border-radius:50%}.orb-main{width:min(34vw,500px);height:min(34vw,500px);left:8%;top:15%;background:radial-gradient(circle at 34% 28%,#efffea,#9be5bc 38%,#327b73 72%,#0b4147);box-shadow:0 45px 80px rgba(3,56,54,.2),inset -25px -20px 40px rgba(4,50,57,.18);animation:float 7s ease-in-out infinite}.orb-main:after{content:"";position:absolute;inset:6%;border:1px solid rgba(255,255,255,.45);border-radius:50%}.orbit{position:absolute;inset:16%;border:1px solid rgba(255,255,255,.6);border-radius:50%;transform:rotate(20deg)}.orbit-b{inset:25% 10%;transform:rotate(105deg)}.orbit i{width:10px;height:10px;border-radius:50%;background:var(--lime);position:absolute;left:12%;top:20%;box-shadow:0 0 15px var(--lime)}.orbit i:nth-child(2){left:78%;top:68%}.orbit i:nth-child(3){left:62%;top:1%}.nucleus{position:absolute;inset:35%;display:flex;flex-direction:column;align-items:center;justify-content:center;border-radius:50%;background:rgba(4,55,61,.82);color:white;text-align:center;box-shadow:0 8px 25px rgba(0,0,0,.2)}.nucleus span{font:700 25px "Manrope"}.nucleus small{text-transform:uppercase;letter-spacing:1.4px;font-size:7px}.orb-small{width:48px;height:48px;right:8%;top:16%;background:var(--lime);box-shadow:0 14px 35px rgba(12,75,72,.2)}.molecule-line{position:absolute;width:100%;height:100%;inset:0;overflow:visible}.molecule-line path{fill:none;stroke:rgba(13,74,81,.28);stroke-width:1.5;stroke-dasharray:5 6}.molecule-line circle{fill:var(--teal)}.visual-label{position:absolute;display:flex;gap:10px;z-index:2;font-size:10px;line-height:1.3;text-transform:uppercase;letter-spacing:1px}.visual-label b{color:#21906f}.label-one{left:5%;bottom:16%}.label-two{right:10%;bottom:25%}.section{padding:clamp(85px,10vw,150px) clamp(24px,7vw,110px)}.section-kicker{color:#47817c}.section-kicker.light{color:var(--mint)}.intro-grid{display:grid;grid-template-columns:1.2fr .8fr;gap:10vw}.section h2{font-size:clamp(38px,4.7vw,66px);line-height:1.08;letter-spacing:-3px;margin:0}.section h2 em{color:#2b836e}.intro-grid p{color:var(--muted);max-width:560px}.intro-grid .lead{font-size:20px;color:var(--ink)}.solutions{background:var(--deep);color:white}.section-heading{display:flex;align-items:end;justify-content:space-between;margin-bottom:65px}.section-heading h2 em,.contact h2 em{color:var(--mint)}.section-heading>p{max-width:390px;color:#a7c0c2}.solution-grid{display:grid;grid-template-columns:repeat(3,1fr);border:1px solid rgba(255,255,255,.14)}.solution-card{min-height:440px;padding:30px;display:flex;flex-direction:column;border-right:1px solid rgba(255,255,255,.14);transition:.3s}.solution-card:last-child{border:0}.solution-card:hover{background:rgba(255,255,255,.06);transform:translateY(-5px)}.solution-card.featured{background:#0e555b}.card-number{font-size:11px;color:#8eb0b3}.card-icon{width:70px;height:70px;margin:auto 0 30px;display:grid;place-items:center;font-size:50px;color:var(--mint)}.enzyme-icon{position:relative}.enzyme-icon i{position:absolute;width:58px;height:20px;border:1px solid var(--mint);border-radius:50%;transform:rotate(25deg)}.enzyme-icon i:nth-child(2){transform:rotate(85deg)}.enzyme-icon i:nth-child(3){transform:rotate(145deg)}.solution-card h3{font-size:24px;margin-bottom:12px}.solution-card p{font-size:14px;color:#afc5c7}.solution-card a{font-size:12px;font-weight:700;margin-top:15px}.solution-card a span{float:right}.applications-layout{display:grid;grid-template-columns:1fr 1fr;gap:10vw}.applications-layout>div>p{max-width:500px;color:var(--muted);font-size:18px;margin-top:32px}.application-list{border-top:1px solid var(--line)}.application-list>div{display:grid;grid-template-columns:50px 1fr 30px;align-items:center;border-bottom:1px solid var(--line);padding:26px 0}.application-list span{font-size:11px;color:#559085}.application-list h3{font-size:19px;margin:0}.application-list i{font-style:normal;transition:.2s}.application-list>div:hover i{transform:translate(4px,-4px)}.quality{display:grid;grid-template-columns:1fr 1fr;padding-top:0}.quality-visual{min-height:530px;background:var(--mint);position:relative;display:grid;place-items:center;overflow:hidden}.rings{width:310px;height:310px;border:1px solid rgba(7,54,61,.25);border-radius:50%;position:relative;display:grid;place-items:center}.rings span{position:absolute;border:1px solid rgba(7,54,61,.25);border-radius:50%;width:75%;height:75%}.rings span:nth-child(2){width:48%;height:48%}.rings span:nth-child(3){width:22%;height:22%;background:var(--teal)}.rings b{font-size:24px;color:white;z-index:1}.quality-visual small{position:absolute;left:30px;bottom:28px;text-transform:uppercase;letter-spacing:1.4px;font-weight:700;font-size:9px}.quality-copy{background:white;padding:clamp(45px,7vw,100px)}.quality-copy p{color:var(--muted);margin:30px 0}.quality-copy ul{list-style:none;padding:0}.quality-copy li{padding:13px 0;border-bottom:1px solid var(--line);font-size:14px}.quality-copy li span{color:#23806b;margin-right:12px}.contact{background:#0d4a51;color:white;display:grid;grid-template-columns:1fr 1fr;gap:10vw}.contact-copy p{color:#b7ccce;max-width:520px;margin:28px 0}.contact-copy>a{font-weight:700;border-bottom:1px solid var(--mint);padding-bottom:4px}.contact-copy>a span{margin-left:18px}.contact-form{background:white;color:var(--ink);padding:36px}.field-row{display:grid;grid-template-columns:1fr 1fr;gap:20px}.contact-form label{font-size:11px;font-weight:700;text-transform:uppercase;letter-spacing:1px;display:block;margin-bottom:20px}.contact-form input,.contact-form textarea{width:100%;border:0;border-bottom:1px solid #bcc8c8;padding:12px 0;font:15px "DM Sans";outline:0;resize:vertical;text-transform:none;letter-spacing:0;background:white;border-radius:0}.contact-form input:focus,.contact-form textarea:focus{border-color:var(--teal)}.button-light{background:var(--mint);color:var(--deep);width:100%}.button-light:hover{background:var(--lime)}.form-note{font-size:12px;margin:12px 0 0;color:#217861}footer{padding:55px clamp(24px,7vw,110px) 30px;background:#082e34;color:white;display:grid;grid-template-columns:1.3fr 1fr 1fr;gap:30px;align-items:center}.footer-brand .brand-mark i{border-color:var(--mint)}footer>p{color:#8eaaad;font-size:13px;margin:0}.footer-links{display:flex;gap:24px;justify-content:end;font-size:13px}.footer-links a:hover{color:var(--mint)}footer>small{grid-column:1/-1;border-top:1px solid rgba(255,255,255,.12);padding-top:25px;color:#708e91;font-size:10px}.reveal{opacity:0;transform:translateY(20px);transition:opacity .7s ease,transform .7s ease}.reveal.visible{opacity:1;transform:none}@keyframes float{50%{transform:translateY(-15px) rotate(2deg)}}
@media(max-width:900px){.site-header{height:72px}.menu-toggle{display:flex;flex-direction:column;gap:7px;padding:10px}.menu-toggle span{width:25px;height:2px;background:var(--ink)}.nav{position:absolute;left:0;right:0;top:72px;background:var(--cream);padding:25px;flex-direction:column;align-items:stretch;transform:translateY(-130%);transition:.3s;z-index:-1;border-bottom:1px solid var(--line)}.nav.open{transform:none}.nav-cta{justify-content:space-between}.hero{grid-template-columns:1fr;padding-left:24px;background:var(--cream)}.hero-copy{padding:70px 24px 50px 0}.hero-visual{min-height:530px;margin-left:-24px;background:#d9f5df}.orb-main{width:370px;height:370px;left:calc(50% - 185px)}.trust-row{gap:18px;justify-content:space-between}.intro-grid,.applications-layout,.quality,.contact{grid-template-columns:1fr}.section-heading{display:block}.section-heading>p{margin-top:25px}.solution-grid{grid-template-columns:1fr}.solution-card{min-height:340px;border-right:0;border-bottom:1px solid rgba(255,255,255,.14)}.quality-visual{min-height:430px}.field-row{grid-template-columns:1fr}footer{grid-template-columns:1fr}.footer-links{justify-content:start}footer>small{grid-column:1}}
@media(max-width:520px){h1{font-size:49px;letter-spacing:-3px}.hero-actions{align-items:flex-start;flex-direction:column}.trust-row{flex-wrap:wrap}.orb-main{width:300px;height:300px;left:calc(50% - 150px);top:20%}.hero-visual{min-height:440px}.section{padding:80px 24px}.section h2{letter-spacing:-2px}.contact-form{padding:25px}.rings{width:250px;height:250px}.quality-visual{min-height:360px}}
.product-strip{margin-top:56px;display:grid;grid-template-columns:repeat(4,1fr);border:1px solid var(--line)}.product-strip span{padding:22px;text-align:center;text-transform:uppercase;letter-spacing:1.3px;font-size:11px;font-weight:700;border-right:1px solid var(--line);background:rgba(255,255,255,.35)}.product-strip span:last-child{border-right:0}
@media(max-width:520px){.product-strip{grid-template-columns:1fr 1fr}.product-strip span{border-bottom:1px solid var(--line)}.product-strip span:nth-child(2){border-right:0}}
.contact-details{display:flex;flex-direction:column;align-items:flex-start;gap:18px}.contact-details a{font-weight:700;border-bottom:1px solid var(--mint);padding-bottom:4px}.contact-details a span{margin-left:18px}.contact-details>span{color:#b7ccce;font-size:14px;text-transform:uppercase;letter-spacing:1.4px}
/* Industry impact and responsive refinements */
.industry-impact{background:#e9f3e9}.impact-heading{display:grid;grid-template-columns:1fr 1fr;column-gap:8vw;align-items:end;margin-bottom:55px}.impact-heading .section-kicker{grid-column:1/-1}.impact-heading p{color:var(--muted);max-width:520px;margin:0}.impact-grid{display:grid;grid-template-columns:repeat(3,1fr);border-top:1px solid var(--line);border-left:1px solid var(--line)}.impact-card{padding:34px;min-height:265px;border-right:1px solid var(--line);border-bottom:1px solid var(--line);background:rgba(255,255,255,.42)}.impact-card span{font-size:11px;color:#4c8c7e}.impact-card h3{font-size:21px;margin:42px 0 12px}.impact-card p{font-size:14px;color:var(--muted);margin:0}section{scroll-margin-top:88px}
@media(max-width:1100px){.site-header{padding-left:28px;padding-right:28px}.nav{gap:20px}.hero{padding-left:50px}.hero-copy{padding-right:40px}h1{font-size:58px}.orb-main{width:390px;height:390px;left:calc(50% - 195px)}.section{padding-left:50px;padding-right:50px}.application-list h3{font-size:17px}.product-strip{grid-template-columns:repeat(2,1fr)}.product-strip span:nth-child(2){border-right:0}.product-strip span:nth-child(-n+2){border-bottom:1px solid var(--line)}}
@media(max-width:900px){section{scroll-margin-top:72px}.brand-logo{width:50px;height:50px}.hero{min-height:auto;padding-left:40px}.hero-copy{padding:72px 40px 55px 0}.hero-visual{min-height:460px}.orb-main{width:350px;height:350px;left:calc(50% - 175px);top:10%}.label-one{left:12%}.label-two{right:12%}.section{padding:90px 40px}.intro-grid,.applications-layout{gap:45px}.impact-heading{grid-template-columns:1fr;gap:25px}.impact-heading .section-kicker{grid-column:auto}.impact-grid{grid-template-columns:repeat(2,1fr)}.quality-copy{padding:60px 40px}.contact{gap:55px}.solution-card{min-height:310px}.card-icon{margin-top:45px}}
@media(max-width:600px){.site-header{height:68px;padding:0 16px}.brand{gap:8px}.site-header .brand-logo{width:42px;height:42px}.brand strong{font-size:12px}.brand small{font-size:6px;letter-spacing:2px}.menu-toggle{padding-right:0}.nav{top:68px;padding:22px 18px;gap:17px}.hero{display:block;padding-left:20px}.hero-copy{padding:55px 20px 45px 0}.eyebrow{margin-bottom:18px}h1{font-size:44px;line-height:1.03;letter-spacing:-2.8px}.hero-copy>p{font-size:16px}.hero-actions{margin:30px 0 42px;gap:24px}.button{width:100%;justify-content:space-between}.trust-row{display:grid;grid-template-columns:1fr 1fr;width:100%;gap:18px}.trust-row div:last-child{grid-column:1/-1}.hero-visual{min-height:340px;margin-left:-20px}.orb-main{width:250px;height:250px;left:calc(50% - 125px);top:11%}.orb-small{width:34px;height:34px}.visual-label{display:none}.nucleus span{font-size:18px}.section{padding:70px 20px}.section h2{font-size:37px;letter-spacing:-1.8px}.intro-grid,.applications-layout{gap:32px}.intro-grid .lead,.applications-layout>div>p{font-size:17px}.section-heading{margin-bottom:38px}.solution-card{padding:24px;min-height:300px}.application-list>div{grid-template-columns:34px 1fr 20px;padding:20px 0}.application-list h3{font-size:15px}.product-strip{margin-top:38px}.product-strip span{padding:17px 8px;font-size:9px}.impact-heading{margin-bottom:35px}.impact-grid{grid-template-columns:1fr}.impact-card{min-height:auto;padding:25px}.impact-card h3{margin:28px 0 8px}.quality-visual{min-height:320px}.rings{width:220px;height:220px}.quality-copy{padding:55px 20px}.contact{gap:38px}.contact-form{padding:22px 18px}.contact-details{gap:14px}footer{padding:45px 20px 25px}.footer-links{flex-wrap:wrap;gap:15px 22px}}
.language-toggle{border:1px solid rgba(17,44,53,.28);background:transparent;color:var(--ink);font:700 12px "DM Sans",sans-serif;padding:8px 11px;cursor:pointer;transition:.2s}.language-toggle:hover{background:var(--teal);color:#fff}.lang-zh body,.lang-zh button,.lang-zh input,.lang-zh textarea{font-family:"Microsoft YaHei","PingFang SC",sans-serif}
@media(max-width:900px){.language-toggle{width:100%;padding:11px}.nav .language-toggle{order:5}}
@media(max-width:600px){html,body{max-width:100%;overflow-x:hidden}.hero,.hero-visual{overflow:hidden}.molecule-line{display:none}.orb-small{right:10%}.hero-copy{position:relative;z-index:3}.hero-visual{position:relative;z-index:1}}
@media(max-width:900px){.menu-toggle{position:relative;z-index:61}.nav{position:fixed;top:72px;left:0;right:0;z-index:60;background:#f5f3e9;padding:28px 40px 34px;transform:translateY(-18px);opacity:0;visibility:hidden;pointer-events:none;box-shadow:0 18px 35px rgba(17,44,53,.16);border-bottom:1px solid rgba(17,44,53,.14)}.nav.open{transform:translateY(0);opacity:1;visibility:visible;pointer-events:auto}.nav a:not(.nav-cta){padding:7px 0}.nav-cta{margin-top:5px}.language-toggle{margin-top:2px}}
@media(max-width:600px){.nav{top:68px;padding:24px 20px 28px;gap:12px}.nav a:not(.nav-cta){font-size:16px;padding:5px 0}.nav-cta{width:100%;padding:15px 18px}.language-toggle{padding:10px}.hero-copy{isolation:isolate}}
.resource-links{background:#f5f3e9;display:grid;grid-template-columns:.8fr 1.2fr;gap:8vw;border-top:1px solid var(--line)}.resource-intro h2{font-size:clamp(34px,4vw,56px);line-height:1.08;letter-spacing:-2.5px}.resource-intro h2 em{color:#2b836e}.resource-grid{display:grid;grid-template-columns:1fr 1fr;border-top:1px solid var(--line);border-left:1px solid var(--line)}.resource-grid a{min-height:145px;padding:24px;display:grid;grid-template-columns:1fr auto;align-content:space-between;border-right:1px solid var(--line);border-bottom:1px solid var(--line);transition:.25s}.resource-grid a:hover{background:#d9f5df}.resource-grid span{grid-column:1/-1;color:var(--muted);font-size:11px;text-transform:uppercase;letter-spacing:1.2px}.resource-grid strong{font:700 19px "Manrope",sans-serif}.resource-grid i{font-style:normal;color:#2b836e}
@media(max-width:900px){.resource-links{grid-template-columns:1fr;gap:40px}.resource-grid a{min-height:125px}}
@media(max-width:600px){.resource-grid{grid-template-columns:1fr}.resource-grid a{min-height:110px;padding:20px}}
.enzyme-guide{background:#092f36;color:#fff}.guide-heading{display:grid;grid-template-columns:1fr 1fr;gap:8vw;align-items:end;margin-bottom:60px}.guide-heading .section-kicker{grid-column:1/-1}.guide-heading h2 em{color:var(--mint)}.guide-heading>p{color:#b6cbcd;font-size:17px;margin:0;max-width:580px}.guide-basics{display:grid;grid-template-columns:1fr 1fr;border:1px solid rgba(255,255,255,.14);margin-bottom:45px}.guide-panel{padding:36px;min-height:280px;border-right:1px solid rgba(255,255,255,.14)}.guide-panel:last-child{border-right:0}.guide-number{font-size:11px;color:var(--mint)}.guide-panel h3{font-size:26px;margin:55px 0 14px}.guide-panel p{color:#aec4c6;margin:0}.reaction-feature{display:grid;grid-template-columns:.8fr 1.2fr;background:#0e555b;margin-bottom:45px}.reaction-copy{padding:45px}.reaction-copy h3{font-size:30px;line-height:1.2;margin:0 0 20px}.reaction-copy p{color:#c0d2d3;margin:0}.reaction-diagram{background:var(--mint);color:var(--ink);padding:45px;display:flex;align-items:center;justify-content:center;gap:20px}.reaction-node{background:#fff;padding:22px;min-width:145px;box-shadow:0 10px 25px rgba(7,54,61,.08)}.reaction-node small,.reaction-node strong{display:block}.reaction-node small{text-transform:uppercase;letter-spacing:1px;color:#648077;font-size:8px}.reaction-node strong{font:700 16px "Manrope",sans-serif;margin-top:5px}.reaction-arrow{text-align:center;display:grid;gap:2px}.reaction-arrow b{font-size:30px;color:var(--teal)}.reaction-arrow span,.reaction-arrow small{font-size:9px}.reaction-products{display:flex;align-items:center;gap:12px}.acylase-feature{display:grid;grid-template-columns:.8fr 1.2fr;gap:8vw;background:#f5f3e9;color:var(--ink);padding:45px;margin-bottom:70px}.acylase-feature h3{font-size:27px;line-height:1.2;margin:0}.acylase-feature p{color:var(--muted);margin:0}.process-layout{display:grid;grid-template-columns:.65fr 1.35fr;gap:6vw}.process-intro h3{font-size:30px;line-height:1.2}.process-intro p{color:#aec4c6}.challenge-grid{display:grid;grid-template-columns:1fr 1fr;border-top:1px solid rgba(255,255,255,.14);border-left:1px solid rgba(255,255,255,.14)}.challenge-card{padding:25px;min-height:190px;border-right:1px solid rgba(255,255,255,.14);border-bottom:1px solid rgba(255,255,255,.14)}.challenge-card b{font:700 16px "Manrope",sans-serif}.challenge-card p{font-size:13px;color:#abc2c4;margin:18px 0 0}.challenge-card.action-card{background:var(--mint);color:var(--ink)}.challenge-card.action-card p{color:#416266}
@media(max-width:1000px){.guide-heading,.process-layout{grid-template-columns:1fr;gap:30px}.guide-heading .section-kicker{grid-column:auto}.reaction-feature{grid-template-columns:1fr}.reaction-diagram{min-height:280px}.acylase-feature{grid-template-columns:1fr;gap:25px}}
@media(max-width:700px){.guide-basics{grid-template-columns:1fr}.guide-panel{min-height:auto;padding:26px;border-right:0;border-bottom:1px solid rgba(255,255,255,.14)}.guide-panel h3{margin:32px 0 12px;font-size:22px}.reaction-copy{padding:30px 24px}.reaction-diagram{padding:28px 18px;display:grid;grid-template-columns:1fr;gap:14px}.reaction-node{min-width:0;width:100%}.reaction-arrow b{transform:rotate(90deg);line-height:1}.reaction-products{display:grid;grid-template-columns:1fr auto 1fr;width:100%}.reaction-products .reaction-node{height:100%}.acylase-feature{padding:28px 22px;margin-bottom:55px}.challenge-grid{grid-template-columns:1fr}.challenge-card{min-height:auto}.process-intro h3{font-size:26px}}
/* Editorial science-led redesign */
:root{--cream:#f8f8f3;--mint:#ccebd7;--lime:#dff5a5}.site-header{position:sticky;top:0;background:rgba(248,248,243,.96);backdrop-filter:blur(12px)}.hero{min-height:780px;background:linear-gradient(90deg,#f8f8f3 0 60%,#e5efe7 60% 100%)}.hero-copy{max-width:850px}.hero-copy>p{max-width:650px;line-height:1.75}.hero-visual{background:radial-gradient(circle at 48% 42%,#fff 0,rgba(204,235,215,.7) 38%,transparent 68%)}
.story-index{display:grid;grid-template-columns:1.6fr repeat(4,1fr);background:#fff;border-top:1px solid var(--line);border-bottom:1px solid var(--line);padding:0 clamp(24px,7vw,110px)}.story-index__intro,.story-index>a{min-height:145px;padding:25px 22px;border-right:1px solid var(--line);display:flex;flex-direction:column;justify-content:space-between}.story-index__intro{padding-left:0}.story-index__intro span{font-size:10px;text-transform:uppercase;letter-spacing:1.8px;color:#568278}.story-index__intro strong{font:700 17px "Manrope",sans-serif}.story-index>a{display:grid;grid-template-columns:1fr auto;grid-template-rows:auto 1fr;transition:.25s}.story-index>a:hover{background:var(--mint)}.story-index>a b{font-size:9px;color:#699087}.story-index>a span{align-self:end;font:700 14px/1.25 "Manrope",sans-serif}.story-index>a i{font-style:normal;grid-column:2;grid-row:1/-1;align-self:end}
.intro{background:#fff}.intro-grid{border-top:1px solid var(--line);padding-top:48px}.solutions{background:#f1f4ee;color:var(--ink);border-top:1px solid var(--line);border-bottom:1px solid var(--line)}.solutions .section-kicker.light{color:#47817c}.section-heading h2 em{color:#2b836e}.section-heading>p{color:var(--muted)}.solution-grid{border-color:var(--line);background:#fff}.solution-card{border-color:var(--line)}.solution-card:last-child{border-color:var(--line)}.solution-card.featured{background:var(--mint)}.solution-card:hover{background:#e3efe5}.solution-card p{color:var(--muted)}.card-number{color:#55847a}.card-icon{color:var(--teal)}.enzyme-icon i{border-color:var(--teal)}
.applications{background:#fff}.applications-layout{border-top:1px solid var(--line);padding-top:48px}.enzyme-guide{border-top:8px solid var(--mint)}.industry-impact{background:#f6f8f3}.quality{padding-bottom:0}.resource-links{background:#fff}.contact{border-top:8px solid var(--mint)}
@media(max-width:1100px){.story-index{grid-template-columns:1.4fr repeat(2,1fr)}.story-index__intro{grid-row:span 2}.story-index>a{border-bottom:1px solid var(--line)}}
@media(max-width:900px){.hero{min-height:auto;background:#f8f8f3}.story-index{grid-template-columns:1fr 1fr;padding:0 40px}.story-index__intro{grid-column:1/-1;grid-row:auto;min-height:100px;border-bottom:1px solid var(--line)}.story-index>a{min-height:120px}.intro-grid,.applications-layout{padding-top:35px}}
@media(max-width:600px){.story-index{padding:0 20px}.story-index__intro{padding-left:0}.story-index>a{padding:18px 12px;min-height:105px}.story-index>a span{font-size:12px}.hero h1{max-width:350px}.hero-copy>p{line-height:1.65}.intro-grid,.applications-layout{padding-top:28px}}
.learning-centre{margin-top:80px;border-top:1px solid rgba(255,255,255,.18);padding-top:55px;display:grid;grid-template-columns:.7fr 1.3fr;gap:7vw}.learning-title h3{font-size:30px;line-height:1.2}.learning-title p{color:#aec4c6}.faq-list{border-top:1px solid rgba(255,255,255,.18)}.faq-list details{border-bottom:1px solid rgba(255,255,255,.18)}.faq-list summary{list-style:none;cursor:pointer;padding:22px 0;display:flex;justify-content:space-between;gap:20px;font:700 15px "Manrope",sans-serif}.faq-list summary::-webkit-details-marker{display:none}.faq-list summary span{font-size:22px;color:var(--mint);transition:.2s}.faq-list details[open] summary span{transform:rotate(45deg)}.faq-list details p{color:#b5c9cb;padding:0 45px 24px 0;margin:0;font-size:14px}
.commercial-pathways{background:#fff}.commercial-heading{display:grid;grid-template-columns:1fr 1fr;gap:8vw;align-items:end;margin-bottom:55px}.commercial-heading .section-kicker{grid-column:1/-1}.commercial-heading>p{color:var(--muted);margin:0}.pathway-table{border-top:2px solid var(--teal)}.pathway-row{display:grid;grid-template-columns:1fr 1.5fr 1fr 1.5fr;border-bottom:1px solid var(--line)}.pathway-row>*{padding:24px 20px;border-right:1px solid var(--line);margin:0}.pathway-row>*:first-child{padding-left:0}.pathway-row>*:last-child{border-right:0}.pathway-row strong,.pathway-row b{font:700 14px/1.4 "Manrope",sans-serif}.pathway-row span{font-size:13px;color:var(--muted)}.pathway-head{background:#edf3ec}.pathway-head span{font-size:9px;text-transform:uppercase;letter-spacing:1.3px;color:#416f66;font-weight:700}.pathway-note{margin:24px 0 0;color:#78898a;font-size:11px;max-width:760px}
@media(max-width:900px){.learning-centre,.commercial-heading{grid-template-columns:1fr;gap:30px}.commercial-heading .section-kicker{grid-column:auto}.pathway-row{grid-template-columns:1fr 1fr}.pathway-head{display:none}.pathway-row>*{border-bottom:1px solid rgba(17,44,53,.07)}.pathway-row>*:nth-child(2){border-right:0}.pathway-row>*:first-child{padding-left:20px}}
@media(max-width:600px){.learning-centre{margin-top:60px;padding-top:40px}.learning-title h3{font-size:25px}.faq-list summary{font-size:14px}.faq-list details p{padding-right:0}.pathway-row{grid-template-columns:1fr}.pathway-row>*{padding:15px 0;border-right:0}.pathway-row>*:first-child{padding:22px 0 8px;color:var(--teal)}.pathway-row>*:last-child{padding-bottom:22px}.pathway-row span{font-size:13px}.pathway-row b:before{content:"Target: ";font-weight:500;color:var(--muted)}}
.hero-art,.quality-art{display:block;width:100%;height:100%;object-fit:cover}.hero-art{position:absolute;inset:0;object-position:center}.hero-visual .orb,.hero-visual .molecule-line,.hero-visual .visual-label{display:none}.hero-visual:after{content:"";position:absolute;inset:0;pointer-events:none;background:linear-gradient(90deg,rgba(229,239,231,.12),transparent 35%)}.quality-art{position:absolute;inset:0;object-position:center}.quality-visual .rings{display:none}.quality-visual:after{content:"";position:absolute;inset:0;box-shadow:inset 0 0 0 1px rgba(17,44,53,.08);pointer-events:none}.quality-visual small{z-index:2;background:rgba(248,248,243,.86);padding:10px 12px;color:var(--ink)}
@media(max-width:900px){.hero-art{object-position:center}.hero-visual{background:#e5efe7}.quality-art{object-position:center 45%}}
@media(max-width:600px){.hero-art{object-fit:cover}.hero-visual{min-height:360px}.quality-art{object-fit:cover}.quality-visual{min-height:360px}}
/* Restored original artwork with video-like 3D motion */
.hero-art,.quality-art{display:none}.hero-visual{perspective:1100px;transform-style:preserve-3d;overflow:hidden}.hero-visual .orb{display:block}.hero-visual .molecule-line{display:block}.hero-visual .visual-label{display:flex}.hero-visual:after{background:radial-gradient(circle at 50% 48%,rgba(255,255,255,.18),transparent 58%)}.orb-main{animation:enzymeFloat3d 8s ease-in-out infinite;transform-style:preserve-3d;will-change:transform}.orbit-a{animation:orbitSpinA 12s linear infinite;transform-style:preserve-3d}.orbit-b{animation:orbitSpinB 9s linear infinite reverse;transform-style:preserve-3d}.orbit i{animation:nodeGlow 2.4s ease-in-out infinite}.orbit i:nth-child(2){animation-delay:-.8s}.orbit i:nth-child(3){animation-delay:-1.6s}.nucleus{animation:nucleusPulse 3.6s ease-in-out infinite}.orb-small{animation:satelliteFloat 5s ease-in-out infinite}.molecule-line path{animation:reactionFlow 7s linear infinite}.molecule-line circle{animation:nodeGlow 2.6s ease-in-out infinite}.label-one{animation:labelDrift 5s ease-in-out infinite}.label-two{animation:labelDrift 5s ease-in-out -2.5s infinite}
.quality-art{display:none}.quality-visual{perspective:900px}.quality-visual .rings{display:grid;transform-style:preserve-3d;animation:qualityTilt 8s ease-in-out infinite}.rings span{animation:ringBreath 4s ease-in-out infinite}.rings span:nth-child(2){animation-delay:-1.3s}.rings span:nth-child(3){animation-delay:-2.6s}.rings:after{content:"";position:absolute;left:calc(50% - 6px);top:-6px;width:12px;height:12px;border-radius:50%;background:#c89d3d;box-shadow:0 0 18px rgba(200,157,61,.65);transform-origin:6px 161px;animation:qualityOrbit 7s linear infinite}.quality-visual:after{box-shadow:inset 0 0 80px rgba(7,54,61,.08)}
@keyframes enzymeFloat3d{0%,100%{transform:translate3d(0,0,0) rotateX(0) rotateY(-2deg)}50%{transform:translate3d(0,-18px,34px) rotateX(3deg) rotateY(5deg)}}@keyframes orbitSpinA{from{transform:rotateX(66deg) rotateZ(20deg)}to{transform:rotateX(66deg) rotateZ(380deg)}}@keyframes orbitSpinB{from{transform:rotateY(68deg) rotateZ(105deg)}to{transform:rotateY(68deg) rotateZ(465deg)}}@keyframes nodeGlow{0%,100%{filter:brightness(1);box-shadow:0 0 10px var(--lime)}50%{filter:brightness(1.35);box-shadow:0 0 24px var(--lime)}}@keyframes nucleusPulse{0%,100%{transform:scale(1);box-shadow:0 8px 25px rgba(0,0,0,.2)}50%{transform:scale(1.07);box-shadow:0 12px 38px rgba(216,255,142,.28)}}@keyframes satelliteFloat{0%,100%{transform:translate3d(0,0,0)}50%{transform:translate3d(-18px,24px,45px)}}@keyframes reactionFlow{to{stroke-dashoffset:-110}}@keyframes labelDrift{0%,100%{transform:translateY(0)}50%{transform:translateY(-8px)}}@keyframes qualityTilt{0%,100%{transform:rotateX(3deg) rotateY(-5deg) translateZ(0)}50%{transform:rotateX(-4deg) rotateY(6deg) translateZ(28px)}}@keyframes ringBreath{0%,100%{opacity:.55;transform:scale(1)}50%{opacity:1;transform:scale(1.045)}}@keyframes qualityOrbit{to{transform:rotate(360deg)}}
@media(max-width:600px){.hero-visual .molecule-line,.hero-visual .visual-label{display:none}.orb-main{animation-duration:7s}.quality-visual .rings{animation-duration:7s}}@media(prefers-reduced-motion:reduce){.orb-main,.orbit-a,.orbit-b,.orbit i,.nucleus,.orb-small,.molecule-line path,.molecule-line circle,.visual-label,.quality-visual .rings,.rings span,.rings:after{animation:none!important}}
.reaction-schemes{display:grid;grid-template-columns:1fr 1fr;gap:1px;background:var(--line);border:1px solid var(--line)}.scheme-card{background:#f8f8f3;padding:30px;min-height:330px;display:flex;flex-direction:column}.scheme-card.scheme-featured{background:#e7f1e7}.scheme-id{font-size:9px;text-transform:uppercase;letter-spacing:1.4px;color:#4e7d73;font-weight:700}.scheme-equation{margin:auto 0;display:grid;grid-template-columns:minmax(100px,1fr) minmax(105px,.75fr) minmax(120px,1.15fr);align-items:center;gap:14px}.chemical-node{background:#fff;border:1px solid rgba(13,74,81,.18);padding:18px 14px;text-align:center;box-shadow:0 8px 24px rgba(17,44,53,.05)}.chemical-node small,.chemical-node strong{display:block}.chemical-node small{font-size:8px;text-transform:uppercase;letter-spacing:1px;color:#69817d}.chemical-node strong{font:700 14px/1.35 "Manrope",sans-serif}.chemical-node.product{border-color:#70a99b;background:#fff}.scheme-arrow{text-align:center;display:flex;flex-direction:column;align-items:center}.scheme-arrow small{font-size:8px;line-height:1.25;color:#52756f;min-height:30px}.scheme-arrow b{font:400 34px/1 "DM Sans",sans-serif;color:var(--teal);width:100%;overflow:hidden}.scheme-result{display:grid;grid-template-columns:1fr auto 1fr;align-items:center;gap:7px}.scheme-result i{font-style:normal;font-weight:700;color:#4e7d73}.scheme-result .chemical-node{padding-left:8px;padding-right:8px}.scheme-result.substrates{grid-template-columns:1fr auto 1fr}.pathway-note{border-left:2px solid var(--mint);padding-left:14px}
@media(max-width:1050px){.reaction-schemes{grid-template-columns:1fr}.scheme-card{min-height:290px}}
@media(max-width:600px){.scheme-card{padding:24px 18px;min-height:auto}.scheme-equation{grid-template-columns:1fr;margin:30px 0 5px}.scheme-arrow{gap:2px}.scheme-arrow small{min-height:auto}.scheme-arrow b{transform:rotate(90deg);font-size:28px}.scheme-result,.scheme-result.substrates{width:100%}.chemical-node{padding:15px 10px}.chemical-node strong{font-size:13px}}
/* Molecular artwork with challenge/solution overlays */
.molecular-hero-art{position:absolute;inset:-3%;width:106%;height:106%;object-fit:cover;object-position:center;display:block;animation:molecularCamera 14s ease-in-out infinite alternate;will-change:transform}.hero-visual .orb,.hero-visual .molecule-line{display:none}.hero-visual .visual-label{display:flex;z-index:4;background:rgba(248,248,243,.86);backdrop-filter:blur(8px);border:1px solid rgba(17,44,53,.12);padding:13px 15px;box-shadow:0 10px 28px rgba(17,44,53,.1)}.hero-visual .visual-label b{color:#1d796a}.hero-visual:after{z-index:2;background:linear-gradient(180deg,rgba(248,248,243,.04),rgba(13,74,81,.08))}@keyframes molecularCamera{0%{transform:scale(1) translate3d(-.5%,0,0)}50%{transform:scale(1.045) translate3d(1%,-1%,0)}100%{transform:scale(1.085) translate3d(-1%,1%,0)}}
@media(max-width:900px){.molecular-hero-art{object-position:center}.hero-visual .label-one{left:30px;bottom:28px}.hero-visual .label-two{right:30px;bottom:28px}}
@media(max-width:600px){.hero-visual .visual-label{display:flex;padding:9px 10px;font-size:8px;background:rgba(248,248,243,.9)}.hero-visual .label-one{left:14px;bottom:14px}.hero-visual .label-two{right:14px;bottom:14px}.molecular-hero-art{animation-duration:12s}}
@media(prefers-reduced-motion:reduce){.molecular-hero-art{animation:none}}
/* Seamless hero composition */
@media(min-width:901px){.hero{position:relative;display:block;min-height:780px;padding-left:clamp(24px,7vw,110px);background:#f8f8f3;isolation:isolate}.hero-copy{position:relative;z-index:5;width:58%;max-width:850px;padding-right:5vw}.hero-visual{position:absolute;z-index:1;inset:0 0 0 34%;min-height:100%;margin:0;background:transparent;-webkit-mask-image:linear-gradient(90deg,transparent 0%,rgba(0,0,0,.12) 8%,#000 30%);mask-image:linear-gradient(90deg,transparent 0%,rgba(0,0,0,.12) 8%,#000 30%)}.hero:after{content:"";position:absolute;z-index:2;inset:0;pointer-events:none;background:linear-gradient(90deg,#f8f8f3 0%,rgba(248,248,243,.98) 30%,rgba(248,248,243,.72) 45%,rgba(248,248,243,.08) 65%,transparent 78%)}.molecular-hero-art{object-position:center right}.hero-visual .label-one{left:24%;bottom:9%}.hero-visual .label-two{right:7%;bottom:18%}}
@media(max-width:900px){.hero{background:#f8f8f3}.hero-visual{-webkit-mask-image:linear-gradient(180deg,rgba(0,0,0,.25) 0%,#000 18%);mask-image:linear-gradient(180deg,rgba(0,0,0,.25) 0%,#000 18%);border-top:0}.hero-copy{margin-bottom:-1px}.hero-visual:before{content:"";position:absolute;z-index:3;inset:0 0 auto 0;height:75px;background:linear-gradient(180deg,#f8f8f3,transparent);pointer-events:none}}
@media(max-width:600px){.hero-visual{margin-top:0}.hero-copy{padding-bottom:35px}.hero-visual:before{height:60px}}
/* Fixed global header */
body{padding-top:88px}.site-header{position:fixed!important;top:0;left:0;right:0;width:100%;z-index:1000;box-shadow:0 1px 0 rgba(17,44,53,.1),0 8px 24px rgba(17,44,53,.04)}section{scroll-margin-top:108px}.admin-bar .site-header{top:32px}.admin-bar section{scroll-margin-top:140px}
@media(max-width:900px){body{padding-top:72px}.site-header{height:72px}.nav{z-index:999}.menu-toggle{z-index:1001}section{scroll-margin-top:92px}.admin-bar .site-header{top:32px}.admin-bar .nav{top:104px}.admin-bar section{scroll-margin-top:124px}}
@media(max-width:782px){.admin-bar .site-header{top:46px}.admin-bar .nav{top:118px}.admin-bar section{scroll-margin-top:138px}}
@media(max-width:600px){body{padding-top:68px}.site-header{height:68px}.nav{top:68px}section{scroll-margin-top:88px}.admin-bar .nav{top:114px}.admin-bar section{scroll-margin-top:134px}}
@media(max-width:520px){.brand-logo{width:48px;height:48px}.brand strong{font-size:14px}}